The thing I like about the Cortex and other HDCs for that matter is that you still have the set of controlls very much like a traditional twin CD unit. I understand that you can get controllers for PCs but is there really any need to do that because its just another bit of kit, with the Cortex the hub and drive can be mounted inside the rear of flight cases and the keyboard can go on a slide out tray so its all very neat. And...I agree keep the front port clear for a stick or whatever. I use the Denon one but TBH the Cortex would suit me fine, I get a lot of folk amazed wehn they ask for a request and I pull out the keyboard and tell them more or less instantly if I have it and I can have it playing before they are back across the dance floor.
Once you get into the swing of it its easy to use and to keep the drive up to date, but I also agree that tagging and file structure is very important...little things like removing the word the from titles is helpful when searching...therefore "the way you make me feel" becomes "way you make me feel"